Efficiency of French football clubs and its dynamics

In the paper we evaluate the efficiency of French football clubs (Ligue 1) from 2004 to 2007 using Data Envelopment Analysis (DEA) with « Assurance Region ». Then, we study the dynamics of clubs’ performances. Contrary to previous works on other championships, best teams in competition or most profitable clubs are not the most efficient units in our sample. High average scores show that French First League is efficient. The first source of inefficiency in the Ligue 1 is linked to size problems and over-investments. Despite an average club performance stable over the period, we exhibit a deterioration of conditions in which clubs operate.Ligue 1, efficiency scores, Data Envelopment Analysis (DEA), Malmquist index, over-investment

Efficiency of French football clubs and its dynamics

In the paper we evaluate the efficiency of French football clubs (Ligue 1) from 2004 to 2007 using Data Envelopment Analysis (DEA) with « Assurance Region ». Then, we study the dynamics of clubs’ performances. Contrary to previous works on other championships, best teams in competition or most profitable clubs are not the most efficient units in our sample. High average scores show that French First League is efficient. The first source of inefficiency in the Ligue 1 is linked to size problems and over-investments. Despite an average club performance stable over the period, we exhibit a deterioration of conditions in which clubs operate

A new autosomal dominant eye and lung syndrome linked to mutations in TIMP3 gene

To revisit the autosomal dominant Sorsby fundus dystrophy (SFD) as a syndromic condition including late-onset pulmonary disease. We report clinical and imaging data of ten affected individuals from 2 unrelated families with SFD and carrying heterozygous TIMP3 mutations (c.572A > G, p.Y191C, exon 5, in family 1 and c.113C > G, p.S38C, exon 1, in family 2). In family 1, all SFD patients older than 50 (two generations) had also a severe emphysema, despite no history of smoking or asthma. In the preceding generation, the mother died of pulmonary emphysema and she was blind after the age of 50. Her two great-grandsons (<20 years), had abnormal Bruch Membrane thickness, a sign of eye disease. In family 2, eye and lung diseases were also associated in two generations, both occurred later, and lung disease was moderate (bronchiectasis). This is the first report of a syndromic SFD in line with the mouse model uncovering the role of TIMP3 in human lung morphogenesis and functions. The TIMP3 gene should be screened in familial pulmonary diseases with bronchiectasis, associated with a medical history of visual loss. In addition, SFD patients should be advised to avoid tobacco consumption, to practice sports, and to undergo regular pulmonary examinations

Wage dispersion and team performance: a theoretical model and evidence from baseball

International audienceWe develop a general theoretical model of the effect of wage dispersion on team performance which nests two possibilities: wage inequality may have either negative or positive effects on team performance. A parameter which captures the marginal cost of effort, which we estimate using game-level data from Major League Baseball, determines whether wage dispersion and team performance are negatively or positively related. We find low marginal cost of effort; consequently, wage disparity is negatively related to team performance. Game and season-level regressions also indicate a negative relationship between inequality and performance. We discuss a variety of interpretations of our results

Comparison of therapeutic evaluation criteria in FDG-PET/CT in patients with diffuse large-cell B-cell lymphoma: Prognostic impact of tumor/liver ratio

International audienceThe study objective was to compare the prognostic value of interim and end-of-treatment FDG PET/CT using five therapeutic evaluation criteria in patients with diffuse large B cell lymphoma (DLBCL)

Combination of baseline FDG-PET/CT total metabolic tumor volume and gene-expression profile have a robust predictive value in patients with diffuse large B-cell lymphoma

International audienc

Combination of baseline FDG-PET/CT total metabolic tumor volume and gene-expression profile have a robust predictive value in patients with diffuse large B-cell lymphoma

International audienc

Tumor fragmentation estimated by volume surface ratio of tumors measured on 18F-FDG PET/CT is an independent prognostic factor of diffuse large B-cell lymphoma

International audienc

I-LowVarFreq: improving low-frequency variant detection using a new UMI-based variant calling approach for paired-end sequencing NGS libraries

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